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It is about in the very big majority of the cases of cancers of the pancreas exocrine.

He especially observes himself after 40 years and especially at the man.

He can touch the head of the pancreas in 80% of the cases, or the body and the tail of the pancreas.

  ..Cancer of the pancreas Reasons and factors of risk

The reason is unknown of it.

He would be more frequent at the diabetic and in case of chronic pancréatite.

Some encouraging factors would be in reason:

  Tobacco;

  A regime rich in greases and in animal proteins.

  ..Cancer of the pancreas The signs of the illness

Two sorts of unrest can reveal the cancer of the pancreas:  of the signs of compression and the signs of secretory insufficiency.

Indeed, the pancreatic tumor is going to compress the organs of neighborhood:  biliary way, stomach, duodenum, nervous plexus, vessels...

The pancreatic secretion insufficiency provokes a fat diarrhea (stéatorrhée). An attack associated of the endocrine pancreas provokes a diabetes.

Three symptoms dominate:

  The jaundice (ictère by retention) especially in the cancer of the head of the pancreas. The gall bladder is distended and palpable.

  Of the violent pains radiating in the back and under the coasts on the left, sometimes calmed when the patient bends forward (antéflexion) or when he takes the aspirin.

  A thinning.

  In the cancer of the body and the tail of the pancreas, the liver is often very voluminous. He/it can have the varicose veins oesophagiennes, a big spleen, there.

  ..Cancer of the pancreas Exams and complementary analyses

The biologic exams understand:  blood sugar and hyperglyceamia provoked by oral way, amylasémie and amylasurie, hepatic balance, dosage of the stéatorrhée, duodenal intubation.

The carcino-embryonic antigen is sometimes increased.

The antigens THAT 19.9 and THAT 50 are useful during the surveillance, but they are not specific.

The signs of tumorous compression can be seen by x-ray of the biliary ways but the tumor can be put in evidence by échotomographie, scanning, or retrograde cholangiopancréatographie by endoscopic catheterization of the bulb of Vater.

The laparoscopie is sometimes necessary to the diagnosis.

  ..Cancer of the pancreas  Treatment

According to the seat of the tumor, the surgeon removes:

  The tail of the pancreas with the spleen in case of cancer of the tail;

  The whole pancreas (total pancréatectomie);

  A cephalic duodéno-pancréatectomie (DPC) in case of cancer of the head with anastomose to the jéjunum of the stomach, the channel cholédoque and the channel of Wirsung.

One possibly uses surgical processes (biliary derivation and/or gastro-entérostomie), some medicines:  analgesics, Questran, pancreatic excerpts, chemotherapy, radiotherapy,.

The endocrine tumors of the pancreas

They are rare. They can be isolated or integrate in a multiple endocrine néoplasie. The symptoms are function of the hormone secreted:

  Insulin:  hypoglycemias;

  Gastrine:  syndrome of Zollinger-Ellison with diarrheas and digestive ulcers;

  Polypeptide intestinal vasoactif (VIP):  syndrome of Verner-Morrison or pancreatic cholera (intense diarrhea)

  Glucagon:  diabetes.

  Somatostatine (diabetes, stéatorrhée).

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