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Of the American researchers identified a gene, named Apobec3, that plays a key role in the production of antibody. These neutralize the rétrovirus, as the VIH, responsible of the AIDS. This discovery has been made among mice but this gene could play the same role at the humans. A hope for the clarification of a vaccine against the VIH. The Apobec3 gene controls alone the capacity of the mice to produce the antibodies neutralizing the rétrovirus, what allows them to fight the infections with success. There is what of the researchers of the Gladstone Institute discovered of virology and immunology of the university of California. Their hypothesis? This gene could have the same role at the human beings and could neutralize the virus of the AIDS. Especially likely hypothesis than previous studies showed that the proteins produced by Apobec3 have some anti-VIH properties and that the region of the chromosome where is this gene exercises an influence on the capacity of the virus to infect the organism. This gene could explain why some people exposed to the virus of the AIDS are never infected.
Other research on the function of the Apobec3 gene at the humans could drive to the discovery of medicines and a vaccine against the AIDS" explains the Dr Anthony Fauci, director of the American national institute of the allergies and the infectious illnesses (NIAID).
The researchers of the NIAID and the Gladstone Institute also discovered that the virus of the AIDS uses one of his proteins, named Quick, to destroy two human proteins produced by the Apobec3 gene. The destruction of these could explain why most individuals don't manufacture an antibody against the virus of the AIDS. The researchers hope as well as the neutralization of the Quick protein will permit to get a stronger immune answer against the virus of the AIDS.
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