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Knee osteoarthritis etiology and treatment of E-mail
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Jumped from the bench, why lower extremity joints bear got? People walking up and down when the lower limb joints of the bones will frictional heat? There have been several millions of years of human evolution, from the extremities to the lower limbs standing crawling-based walking, walking in order to meet the needs of various joints of human lower limbs developed into a very sound level.

Young soldiers can load 50 to 60 kilometers a day on foot, 10 consecutive days, bilateral knee still normal. Marathon runner running each time the amount of training and competitions, up to more than 40 kilometers, bilateral knee still got to bear. Here are the load-bearing role of the lower limb joints around the ligaments, tendons stabilizing effect, joint muscle strength on both sides of the role of the support and movement, intra-articular synovial secretion of the nutritional role of the synovial fluid, in particular mention are the intra-articular bone and joint surfaces cartilage and meniscus on the special role. Articular cartilage and meniscus cartilage in the same cartilage, when the joint compression, it has a buffer pressure, so as to protect against bone and joint injuries; it's shaping reasonable to make weight evenly delivered to the tibia, avoiding excessive tibial plateau at high pressure, thereby protecting the tibial plateau.

Cartilage is divided into hyaline cartilage, fibrous cartilage and bone cartilage, mainly including cartilage cells and matrix, matrix of physical and chemical characteristics by the effects of matrix composition. Clinical osteoarthritis in the elderly is a common chronic cartilage injury arising from diseases. Osteoarthritis mostly occurs in the knee, hip, lumbar, cervical and other parts, of which the highest incidence of knee joint, so we highlight the knee osteoarthritis. Knee Osteoarthritis mostly occurs after the age of 50, women outnumber men. Epidemiological investigation showed that the elderly aged over 55 the incidence of knee osteoarthritis was 44% ~ 70%, in other words, for every two in the elderly, there is a lifetime will suffer from knee bone arthritis. Patients often complained of knee pain, knee pain significantly when the first up and down stairs, squatting knee pain occurs at the same time move to the ground when walking with unilateral or bilateral knee pain. Patients also complained of soreness after walking down the stairs are particularly intensified, and sometimes with swollen knee. X-ray examination of knee pain can be found there is vegetation, intra-articular effusion, and even found that gap narrowed knee.

Why do young people rarely occur, but the elderly are susceptible to osteoarthritis? Why are people more than knee osteoarthritis after exercise easy to attack? Know which factors will affect the cartilage damage?

First, the cartilage tissue in the body is with the existence of life while maintaining metabolism, that is, maintain the dynamic balance of its ingredients. The activities of daily wear and tear caused by intra-articular cartilage is always kept to be compensated, such compensation affected by many factors. Cartilage wear under load increase by more than a compensatory repair capacity of cartilage; affect cartilage regeneration to enhance a variety of factors, including the sex hormones decrease, insufficient essential nutrients, may further delay the cartilage repair.

At present the treatment of osteoarthritis of the knee to take a more comprehensive treatment approach, treatment, include the following:

1.To strengthen cartilage nutrition, enhance the repair capacity of cartilage, such as the use of peacekeeping Guli, hyaluronic acid, sodium and other drugs.

2.Remove the factors that affect the cartilage tissue regeneration, such as estrogen replacement therapy, calcium and so on.

3. The application of anti-inflammatory analgesic drugs. Primarily non-steroidal anti-inflammatory analgesic drug applications, including acetyl salicylic acid (aspirin), paracetamol, diclofenac salts and a variety of new non-steroidal anti-inflammatory analgesic drugs. Traditional medicines have shown this type of gastrointestinal side effects, but a new type of selective cyclooxygenase (COX) inhibitors such as Celebrex, which not only has good anti-inflammatory analgesic effect and stimulate the gastrointestinal tract is very small.

4. Suitable for movement. Because patients with osteoarthritis pain, joint swelling causes a corresponding reduction in joint activities, long-term can lead to muscle atrophy, joint instability, joint load imbalances. Carried out joint activities, appropriate exercise can increase and enhance muscle strength and exercise endurance, so that joints in better mechanical condition of biological activities, in particular, such as walking, tai chi and other exercise, can produce a slight cartilage compression and massage effect is the most suitable form of exercise in patients with osteoarthritis.

5. Other treatments. Such as physical therapy, the use of braces or auxiliary devices.

 

                                                                                                                                                2010-01-17

 

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