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 Collagenous colitis is a newly-recognized disease of the colon. Collagenous colitis is inflammation of the colon, the last portion of the digestive tract that ends at the rectum and anus. The most common symptom is chronic watery, non-bloody diarrhoea. Collagenous colitis is a rare condition that affects about four people in every 10,000. It tends to develop in people aged over 40 years. Women outnumber men 20 to one. There is no cure but lifestyle changes and medical treatment can manage the symptoms in most cases. Collagenous colitis affecting women more than men. Collagenous colitis reason of chronic ulcerative colitis and Crohn's disease. Use of nonsteroidal antiinflammatory drugs (NSAIDs) as a reason of infinitesimal colitis. Some patients' diarrhoea improves after stopping the NSAIDs. Some folk with collagenous colitis too have new autoimmune disorders such as rheumatoid arthritis, scleroderma or Sjogren’s syndrome. The handling of infinitesimal colitis has not been standardized because there have not been sufficient big scale, potential, placebo controlled handling trials. Treatment of collagenous colitis is often challenging, and many agents have been used therapeutically. Trial of lactose elimination (just to eliminate the possibility that intolerance to lactose in milk is aggravating the diarrhea). Anti-diarrhea agents such as Imodium or Lomotil also use this condition. 5-ASA (mesalamine) compounds such as Asacol, Pentasa, or Colazal are helpful this diease. If medications do not control the diarrhea, taking a bismuth subsalicylate such as Pepto-Bismol or Kaopectate. Avoiding certain medications such as nonsteroidal, anti-inflammatory drugs (NSAIDS).In rare cases, the chronic diarrhoea cannot be brought under control and surgery is needed. Diseased sections of the colon may be removed.
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