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Arthritis is the most common chronic diseases, a total of more than 100 kinds of types, the most common are osteoarthritis and rheumatoid arthritis. In severe cases, osteoarthritis may be loss of full mobility, while the course of rheumatoid arthritis for two years, their bone destruction rate of 50%, severe disease shortening life expectancy of about 10 ~ 15 years. Primary cause of osteoarthritis is not clear, is generally believed that with obesity, age, trauma, endocrine, cartilage metabolism, immune abnormalities and genetic and other factors. Among them, easy to add to obese patients weight-bearing joints, induced osteoarthritis. Obese patients in order to maintain focus, it is prone to knee varus deformity, so that gap on both sides of the knee load imbalance, leading to degeneration. Especially the accumulation of minor damage (such as slipping up and down stairs), can cause changes in subchondral bone sclerosis affecting the articular cartilage of the joint weight-bearing resistance, leading to cartilage degeneration, thereby occurring osteoarthritis. With age, the incidence of osteoarthritis gradually increased. According to the research showed that 15 to 44-year-old population, the incidence rate of less than 5%; 45 ~ 64 year old group, the incidence rate was 25.3%; while the population older than 65 years of age, the incidence rate as high as 60%. Especially among older and obese patients is a high risk of osteoarthritis.  Therefore, if the body is not functioning in certain joints feel comfortable with, should think of the possibility of suffering from osteoarthritis, but also may be in early. The common symptoms are: joint stiffness, osteoarthritis patients often feel stiff hands and feet. Some people sedentary, suddenly felt like the joints like a stuck on the lock, often getting up in the morning after the symptoms clear. Joint occurrence Kacha sound, osteoarthritis developed at a later stage due to articular cartilage degradation, spalling, will subchondral bone exposed. Joint activities, at both ends of the exposed subchondral bone, touch each other when their voices heard. Joint deformities, joint synovial distribution of many nerve endings as sensory pain, these pain messages transmitted to the cerebral cortex, the synovial membrane secrete more synovial fluid to provide lubrication of the synovial tissue nourished by the injury. If the increase in joint space fluid, causing swelling and pain will increase, and even joints difficult to turn. In addition, gender and the incidence of osteoarthritis is also closely related. Pre-menopausal women, the incidence of osteoarthritis similar to men; but after menopause, women with osteoarthritis were significantly higher than men. Special occupational groups, such as the squat or squat a long period of miners could easily cause a knee, elbow osteoarthritis occurred; pick cotton or textile factory workers, their hands joint inflammation occurred in the more common; professional sports, and excessive strain will be caused by osteoarthritis. A family history of a small number of patients with osteoarthritis also may be genetic in cartilage matrix synthesis enzyme abnormalities, thereby contributing to the occurrence of osteoarthritis. 2010-01-16
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